HPLC Column Washing by Sonication: When, Why, and How?
HPLC Column Washing by Sonication is used to remove strongly adsorbed materials and improve column performance HPLC columns can be cleaned effectively using sonication, a process that uses ultrasound waves to help remove built-up contaminants. This method is especially helpful for getting rid of strongly adsorbed substances that regular flushing might miss. To clean the […]
Process Validation In Pharmaceutical: Principles, Types, Case Studies And FAQs
Learn about process validation in the pharmaceutical industry, its principles, types, and key case studies. Understand its importance for ensuring product quality, regulatory compliance, and patient safety.
What is the Difference Between Ruggedness And Robustness: Learn In 5 Minutes
Explore the difference between Ruggedness and Robustness testing in pharmaceutical analysis. Learn their importance in ensuring method reliability, consistency, and quality control across varying conditions
Difference Between Analytical Method Development and Validation: Case Studies and 5+ FAQs
Analytical Method Development and Validation: Method Development involves designing a reliable technique to identify and quantify chemical substances, while Analytical Method Validation confirms that this developed method consistently delivers accurate, precise, and reproducible results for its intended purpose. In the world of pharmaceuticals, biotechnology, and chemical manufacturing, analytical methods are essential tools for ensuring the […]
5 Key Differences Between Qualification and Validation: Learn Quickly
Discover the key differences between qualification and validation in the pharmaceutical industry, including real-world case studies, regulatory insights, and FAQs to ensure GMP compliance
Difference Between Reproducibility And Intermediate Precision In Analytical Method Validation
Intermediate precision measures variability within the same laboratory under different conditions (e.g., different days, analysts, instruments), while reproducibility measures variability between different laboratories, assessing method performance across different locations and setups. In the world of analytical chemistry and pharmaceutical quality control, method validation is critical to ensure that data generated from analytical tests is reliable, […]
HPLC Mobile Phase Modifiers: Types, Selection, Case Studies, Expert Tips With 5 FAQs
HPLC Mobile phase modifiers—such as trifluoroacetic acid and triethylamine—are chemical additives incorporated into the mobile phase to enhance peak efficiency, resolution, elution profiles, and selectivity in HPLC separations High-Performance Liquid Chromatography (HPLC) is a cornerstone technique in analytical chemistry for separating, identifying, and quantifying compounds in a mixture. One of the most critical aspects of […]
Key Difference Between GMP and cGMP: Learn Easily In 5 Minutes With FAQs
The key difference between GMP and cGMP is that GMP (Good Manufacturing Practices) refers to established guidelines for manufacturing quality products, while cGMP (current Good Manufacturing Practices) emphasises the ongoing implementation of up-to-date technologies, practices, and regulations to ensure product quality and compliance with evolving industry standards. In this blog, I will discuss the key […]
Why Degassing The Mobile Phase Is Essential In HPLC: Learn In 3 Minutes
Learn why degassing the mobile phase is essential in HPLC. Discover its impact on system performance, accuracy, and the best degassing methods used in modern labs.”
Technology Transfer of Analytical Testing Methods: Purpose, Challenges, and Best Practices
Technology Transfer of Analytical Methods in Pharmaceuticals refers to the systematic process of transferring validated analytical methods from one laboratory (e.g., R&D, method development lab) to another (e.g., quality control, manufacturing site lab), ensuring the method performs equivalently and reliably at the receiving site. Analytical Method Transfer Analytical Method Transfer, also known as Technology Transfer […]