Spectrophotometric Method Development Foundation Course | (UV & FTIR)

Description

Spectrophotometric Method Development Foundation Course (UV & FTIR)

This course provides a strong foundation in the development and application of spectrophotometric analytical methods using UV-Visible spectroscopy and FTIR spectroscopy in pharmaceutical analysis. It focuses on understanding fundamental principles, method development strategies, validation requirements, and regulatory expectations. Participants will learn how to design, optimize, and apply spectrophotometric methods for identification, quantification, and quality control of drug substances and products.

Key Learning Areas

• Fundamentals of UV & FTIR Spectroscopy
  Understanding basic principles, instrumentation, and working mechanisms of UV-Visible and FTIR spectroscopy in pharmaceutical analysis.
• Method Development Principles
  Designing spectrophotometric methods for assay, identification, and impurity detection with focus on accuracy, sensitivity, and specificity.
• Wavelength Selection & Optimization
  Selection of λmax, absorbance range, baseline correction, and optimization of analytical conditions for reliable measurements.
• Sample Preparation Techniques
  Proper preparation of solutions, dilutions, solvent selection, and handling of solid and liquid samples for UV and FTIR analysis.
• Calibration & Quantification Approaches
  Developing calibration curves, ensuring linearity, and applying quantitative methods for assay and content determination.
• Method Validation Parameters
  Understanding key validation elements including linearity, precision, accuracy, robustness, LOD/LOQ, and specificity.
• FTIR Applications in Pharma
  Identification of functional groups, raw material verification, polymorphism detection, and impurity profiling.
• Regulatory Compliance & Data Integrity
  Ensuring compliance with pharmacopeial and ICH guidelines along with proper documentation and data integrity practices.